#Mindview settings portable

A set of mirrors placed in front of the patient׳s eyes (behind the RF coil) will ease the patient׳s sensation of claustrophobia. The coincidence of one PET detector module with 10 opposite modules produces a transaxial FOV of about 24 cm, which ensures complete coverage of the human brain. In order to minimize distortions in the MRI performance, the distance between the shielded PET system and the rungs of the RF conductor area is about 3 cm. The 20 RF coil rungs are integrated in front of the PET system, placed in the junction regions between the modules. This configuration leads to an axial field of view (FOV) of approximately 15 cm and a geometrical PET aperture of ~33 cm in diameter. 1) of LYSO crystals (5 cm×5 cm×2 cm thick) using Silicon PhotoMultiplier (SiPM) arrays as photosensors. This is accomplished by using 3 rings in the axial direction, with 20 modules per ring (see Fig. Based on head size investigations and keeping patient comfort in mind, the geometric aperture of the whole PET/RF device is 26 cm. The dimensions of the system are arrived at as a compromise between the PET imager and the RF-coil performances.

#Mindview settings portable

Both the PET system and a new transmitter/receiver (TR) RF coil (custom made by NORAS MRI, Germany) systems are integrated into a single portable and compact design which is dedicated to brain examination. Furthermore, this compact PET imaging device has to be fully compatible with operation in high magnetic fields in order to allow its integration with most common clinically used MRI scanners. The MINDView project will develop a high resolution and high sensitivity brain-dedicated PET system, capable of visualizing neurotransmitter pathways and their hypothesized disruptions in mental disorders for diagnosis and treatment monitoring. The main technical goal of the Multimodal Imaging of Neurological Disorders (MINDView) project and, thus, the subject of this contribution, is the achievement of simultaneous high-resolution PET/MRI imaging dedicated to brain examination to study psychiatric disorders in the clinical research setting. With spatial resolutions of ~1 mm it will be possible to answer specific questions relating to brain function in small brain regions.

Even for processes localized within the amygdala, it is currently not possible to differentiate if they are occurring within the basolateral complex or the central nucleus. Standard PET/CT (and now also the new PET/MRI) human whole body scanners result in a PET image resolution in the 4–5 mm FWHM range and therefore, are not optimized for imaging small mm-size structures in the brain. The monolithic scintillator showed average detector resolutions varying from 3.5 mm in the entrance layer to better than 1.5 mm near the photosensor, with average energy resolutions of about 17%. It was possible to resolve all pixel elements from the three scintillator layers with energy resolutions as good as 10%. Laboratory test results associated with the current MINDView PET module concept are presented in terms of key parameters׳ optimization, such as spatial and energy resolution, sensitivity and Depth of Interaction (DOI) capability. Two scintillator configurations have been tested, namely a 3-layer staggered array of LYSO with 1.5 mm pixel size, with 35×35 elements (6 mm thickness each) and a black-painted monolithic LYSO block also covering about 50×50 mm 2 active area with 20 mm thickness. When coupled to the new head Radio Frequency (RF) coil, the inner usable diameter of the complete PET-RF coil insert is reduced to 26 cm. The current design for the PET insert consists of a 3-ring configuration with 20 modules per ring and an axial field of view of ~15 cm and a geometrical aperture of ~33 cm in diameter. The proposed design will enable the currently-installed MRI base to be easily upgraded to PET/MRI systems. The PET system should be compact and fully compatible with a Magnetic Resonance Imaging (MRI) device in order to allow its operation as a PET brain insert in a hybrid imaging setup with most MRI scanners. The Multimodal Imaging of Neurological Disorders (MINDView) project aims to develop a dedicated brain Positron Emission Tomography (PET) scanner with sufficient resolution and sensitivity to visualize neurotransmitter pathways and their disruptions in mental disorders for diagnosis and follow-up treatment.